Clinical Tests Showed Efficacy Of Difflam-C® In Relieving COVID-19 Sore Throat

Posted on by

A recent in-vivo study done by the UERM Memorial Medical Center Research team shows Difflam-C®, a locally-available antiseptic gargle solution, significantly alleviates the so-called COVID-19 Sore Throat – the most common symptom and tell-tale sign of people diagnosed with COVID-19.

The in-vivo study focused on establishing whether the combination of Benzydamine HCl and Chlorhexidine gluconate in Difflam-C® are effective in a real-world setting and was conducted on 219 COVID-19 patients from November 2021 until February 2022. This combination of active ingredients found in Difflam-C® solution have been gaining popularity in the Philippines particularly among doctors and healthcare professionals, with the synergistic action of its anti-inflammatory, analgesic, anesthetic, and antiseptic properties in relieving sore throat, as well as other symptoms of throat and mouth infection.

Host Justin Quirino with Dr. Nailes and Dr. Salvino at the Better Days with Difflam Media Roundtable event.

Host Justin Quirino with Dr. Nailes and Dr. Salvino at the Better Days with Difflam Media Roundtable event.

Representatives from iNova Pharma Philippines Inc. (makers of Difflam-C gargle) together with Dr. Jennifer Nailes, MD, and Dr. Roberto Salvino, MD, the doctors who spearheaded the recent study on the effectivity of the Difflam-C gargle against COVID 19-related throat pain, recently held a media roundtable to reveal their study’s findings. Standing from left are:  Michelle dela Cruz, Marketing Manager of iNova Pharma Philippines Inc., Ria Enriquez, Difflam Product Manager; Dr. Jennifer Nailes, vice president for research at University of the East Ramon Magsaysay Memorial Medical Center Inc, Dr. Roberto Salvino, Medical Director, iNova Pharma Philippines Inc., and Eric Yuson, Associate Medical Affairs Manager of iNova.

Clinically-tested Efficacy in COVID-19 Patients

Lead investigators of the study have found that Difflam-C® significantly relieves the COVID-19 patients’ sore throat and alleviated throat discomfort associated with difficulty and/or pain in swallowing. Results also show that it helps shorten the duration of the said condition of COVID-19 patients, with the VAS scores of participants significantly decreased during course of treatment with Difflam-C®. “At specified time intervals, median VAS scores showed a decreasing trend from baseline until after 12 hours of Day 1 and is significantly different from baseline values (p<0.001). There were some participants whose sore throat pain were relieved within 30 minutes of first use of the solution which persisted even until after 12 hours,” said lead investigator Dr. Jennifer M. Nailes, MD, MSPH, Vice-President for Research of the University of the East Ramon Magsaysay Memorial Medical Center, Inc.

Gargle Against COVID-19 Sore Throat

“There was a noticeable shortening of the course of the sore throat in the study subjects, with their use of Difflam-C® during treatment. This gargle solution could be viewed as an effective treatment for patients with odynophagia (painful swallowing) or dysphagia (difficulty swallowing), conditions associated with severe sore throat among COVID-19 patients,” said Dr. Nailes.

Though yet to be published by Acta Medica Philippina, a peer-reviewed general medical and health science journal, these results are extremely encouraging and present a positive step in addressing the COVID-19 sore throat, using a widely available medicated gargle solution such as Difflam-C® in the study.

Better Day bag containing health and wellness items and Difflam-C and Difflam lozenges were given out after the event

Better Day bag containing health and wellness items and Difflam-C and Difflam lozenges were given out after the event

As cases rise and new Omicron variants are discovered, the results of this study could be valuable information in making the public more aware of clinically tested remedies to help address key symptoms like the COVID-19 sore throat. While Benzydamine HCl + Chlorhexidine gluconate (Difflam-C®) could be an effective treatment for COVID-19 sore throat, getting vaccinated with boosters, the observance of standard health protocols, and maintaining a healthy lifestyle are the current mainstays for the prevention of COVID-19 infection.

13 Comments so far. Feel free to join this conversation.

  1. Beth 2022/08/15 at 6:54 pm - Reply

    That’s fantastic. COVID gave me one of the worst sore throats of my life. I consider myself lucky because that was the worst of it, but it still hurt so bad!

  2. Deanna 2022/08/15 at 9:52 pm - Reply

    This is really good to know!

  3. Stephanie 2022/08/16 at 12:30 am - Reply

    I hadn’t heard of this, but if it helps with symptoms that’s great! I know a few people who had it and said the sore throat was the worst part.

  4. Oli 2022/08/16 at 2:08 am - Reply

    That is great news! I am happy to have found out about Difflam-C’s benefits. I will definitely stock up in my medicine cabinet for times of need.

  5. Fransic verso 2022/08/16 at 4:04 pm - Reply

    This is an interesting product and will recommend this to my friend. Thank you for sharing!

  6. Melanie E 2022/08/16 at 5:41 pm - Reply

    It’s good to hear that there is something that is an effective treatment for the sore throat you get with covid. Mine lasted ages and I wish I had something that was effective.

  7. Irena 2022/08/16 at 9:26 pm - Reply

    I need this medication! Just in case!

  8. pooja Malkani 2022/08/17 at 5:40 am - Reply

    Interesting to know about Difflam C relieving Covid symptoms. Such medicines need lot of manufacturing support to be able to help people around the world

  9. Ntensibe Edgar 2022/08/17 at 8:10 am - Reply

    Ooohhhhh…this is good news! I hope Difflam will become cheaper, for us in the under-developed countries.

  10. Rosey 2022/08/17 at 9:07 am - Reply

    I just got over my second case of Covid. It’s not fun and I could live without catching it again, that’s for sure.

  11. Abida 2022/08/17 at 11:01 am - Reply

    When I was corona affected, I suffered a lot from my sore throat. I am happy that people are not going to suffer in the same way now

  12. Marysa 2022/08/17 at 12:44 pm - Reply

    I’ve never heard of this product before. It is nice to know that there is a treatment for sore throats. Sometimes that is the worst and most painful part of being sick!

  13. Angelica 2022/08/17 at 5:10 pm - Reply

    Luckily I didn’t get a sore throat each time I had Covid but this seems like a worthy treatment.

Leave A Response